Shared Personal Protective Equipment (PPE) Resources (S10 Clinical Trial Not Allowed) | PAR 21 257

Opportunity Information: Apply for PAR 21 257

The Shared Personal Protective Equipment (PPE) Resources (S10 Clinical Trial Not Allowed) opportunity (PAR-21-257) is an NIH discretionary grant program intended to help research organizations obtain shared PPE resources that directly support NIH-funded clinical trials and other NIH clinical research activities. The core purpose is practical and operational: to strengthen the ability of research sites and institutions to protect staff and participants and to keep clinical research moving safely by ensuring access to appropriate PPE as a shared resource. The opportunity sits under the NIH health funding activity area (CFDA 93.855) and uses the grant funding instrument.

A key feature of this program is that applications are not generally open for submission on their own. NIH restricts access so that only applications submitted in response to a Notice of Special Interest (NOSI) issued by a specific NIH Institute or Center (IC) are permitted under this funding opportunity announcement (FOA). In other words, applicants must track and respond to an IC-published NOSI that explicitly points to PAR-21-257; without that NOSI pathway, an application would not be considered allowable. The title also highlights an important boundary: "Clinical Trial Not Allowed," meaning the award mechanism itself is not intended to support the conduct of a clinical trial as the proposed project. Instead, the emphasis is on providing shared PPE resources that enable and support existing or ongoing NIH clinical trials and clinical research operations.

Eligibility is broad across the U.S. research and public sector landscape. Eligible applicants include many types of domestic entities such as state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other applicant types as NIH may allow. The FOA also explicitly calls out additional eligible groups, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISI institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, faith-based or community-based organizations, certain eligible federal government agencies, regional organizations, and U.S. territories or possessions.

Foreign eligibility is restricted in a way that matters for planning. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, "foreign components" are allowed as defined by the NIH Grants Policy Statement, meaning a U.S. applicant may be permitted to include certain foreign elements within the project when NIH policy criteria are met, even though a foreign organization cannot serve as the primary applicant.

The FOA was created on June 3, 2021, and the original closing date listed in the source information is May 24, 2022. No award ceiling or expected number of awards is specified in the provided source data, which typically means applicants would need to consult the full FOA text and the relevant IC-issued NOSI for any institute-specific budget limits, application due dates, and program priorities. Overall, the opportunity is best understood as an NIH mechanism to fund shared PPE capacity that directly enables safe execution of NIH clinical trials and clinical research, with access controlled through IC-issued NOSIs and with clinical trial conduct explicitly outside the scope of what can be proposed under this award.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Shared Personal Protective Equipment (PPE) Resources (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
• This funding opportunity was created on 2021-06-03.
• Applicants must submit their applications by 2022-05-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 21 257

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