Opportunity Information: Apply for RFA CA 18 006
The grant opportunity titled "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trials Optional)" (RFA-CA-18-006) is a National Cancer Institute (NCI), National Institutes of Health (NIH) funding announcement designed specifically for revision applications to existing, already-funded NCI R01 projects. Instead of supporting entirely new standalone projects, this FOA targets active R01 awards and provides additional funds so investigators can expand the scope of their parent study, strengthen the original aims, or move the work forward faster by adding a new technology component.
The central goal is to speed up cancer research progress by integrating cutting-edge tools that were developed with support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. In practical terms, applicants are expected to incorporate a new technical approach, platform, instrument, or method that emerged from IMAT funding into their ongoing R01 research. The intent is not just to "try something new," but to meaningfully enhance what the parent award is already doing, either by enabling new lines of inquiry aligned with the original project, improving performance or throughput, increasing sensitivity or precision, or otherwise accelerating discovery and translation within the existing research framework.
A major emphasis of this FOA is independent validation and broader adoption of IMAT-developed technologies. NCI is using these revision awards as an incentive for research groups outside the original technology development teams to test and validate these tools in real-world research settings. By encouraging independent labs and cancer research communities to evaluate and apply emerging IMAT technologies, the program aims to reduce barriers to adoption, establish confidence in performance and utility, and help promising innovations transition from development into widespread use where they can have a larger impact on cancer biology, detection, diagnosis, and treatment research.
This opportunity is offered as an R01 revision with clinical trials listed as optional, meaning applicants may propose work that does or does not involve a clinical trial, as long as it fits NIH definitions and complies with all relevant policies. The award ceiling is listed as $150,000, and the FOA anticipated making about three awards. The funding instrument is a grant, and the activity category is listed under education and health (CFDA 93.394), reflecting its placement within NIH's broader cancer research funding portfolio.
Eligibility is broad and includes many common NIH applicant types: public and private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses, though not limited to them), and multiple levels of government entities (state, county, city/township), as well as special district governments, independent school districts, and Native American tribal governments and organizations. The key practical eligibility constraint implied by the FOA is that applicants must be requesting a revision to a currently funded NCI R01, since the mechanism is built around expanding an active parent award rather than initiating a new project.
Administratively, the FOA was created on December 4, 2017, with an original closing date of September 28, 2018. It is issued by the U.S. Department of Health and Human Services through NIH/NCI. Overall, the program is best understood as a targeted supplement-like revision mechanism intended to quickly inject high-value, NCI-supported innovative technology into ongoing cancer research projects, promote interdisciplinary collaboration around tool adoption and evaluation, and accelerate the pace and reach of scientific discovery by moving validated technologies into the hands of the researchers who can use them immediately.Apply for RFA CA 18 006
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trials Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394.
- This funding opportunity was created on Dec 04, 2017.
- Applicants must submit their applications by Sep 28, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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| NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3, Clinical Trial Optional) Apply for RFA DA 18 020 Funding Number: RFA DA 18 020 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| Administrative Supplements to NCI Grant and Cooperative Agreement Awards to Support Collaborations with the PDX Development and Trial Centers Research Network (PDXNet)(Admin Suppl - Clinical Trial Not Allowed) Apply for PA 18 496 Funding Number: PA 18 496 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
| Identification of Biomarkers of HIV-1 Pathogenesis and Substance Abuse Comorbidity (R01- Clinical Trial Not Allowed) Apply for RFA DA 18 023 Funding Number: RFA DA 18 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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| Administrative Supplements to NCI Grant and Cooperative Agreement Awards to Support Collaborations with the Drug Resistance and Sensitivity Network (DRSN)(Admin Supp Clinical Trial Not Allowed) Apply for PAR 18 752 Funding Number: PAR 18 752 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| NCI Community Oncology Research Program (NCORP) Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 016 Funding Number: RFA CA 18 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Minority/Underserved Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 017 Funding Number: RFA CA 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required) Apply for RFA CA 18 015 Funding Number: RFA CA 18 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Approaches to Identify and Care for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Required) Apply for RFA CA 19 017 Funding Number: RFA CA 19 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| HIV/AIDS High Priority Drug Abuse Research (R01 Clinical Trial Optional) Apply for PAS 18 915 Funding Number: PAS 18 915 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Fusion Oncoproteins in Childhood Cancers (FusOnC2) Consortium (U54 Clinical Trial Not Allowed) Apply for RFA CA 19 016 Funding Number: RFA CA 19 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,600,000 |
| Administrative Supplements to Cancer Center Support Grants to Strengthen the Research, Training, and Outreach Capacity of the Geographic Management of Cancer Health Disparities Program (Admin Suppl - Clinical Trial Not Allowed) Apply for PA 18 934 Funding Number: PA 18 934 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Optional) Apply for RFA DA 19 008 Funding Number: RFA DA 19 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) Apply for PAR 19 032 Funding Number: PAR 19 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Administrative Supplements to Cancer Center Support Grants to Strengthen NCI-Supported Community Outreach Capacity through Community Health Educators of the National Outreach Network (Admin Suppl Clinical Trial Not Allowed) Apply for PA 19 035 Funding Number: PA 19 035 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
| Immuno-Oncology Translation Network (IOTN): Immuno-engineering to Improve Immunotherapy (i3) Centers (U54 Clinical Trial Not Allowed) Apply for RFA CA 19 013 Funding Number: RFA CA 19 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $900,000 |
| HEAL Initiative: Justice Community Opioid Innovation Network (JCOIN) Coordination and Translation Center (U2C Clinical Trial Optional) Apply for RFA DA 19 024 Funding Number: RFA DA 19 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $2,500,000 |
| HEAL Initiative: Justice Community Opioid Innovation Network (JCOIN) Methodology and Advanced Analytics Resource Center (U2C Clinical Trial Not Allowed) Apply for RFA DA 19 023 Funding Number: RFA DA 19 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $2,500,000 |
| NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed) Apply for RFA CA 19 029 Funding Number: RFA CA 19 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required) Apply for RFA CA 19 030 Funding Number: RFA CA 19 030 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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