Opportunity Information: Apply for RFA GH 17 001
The grant opportunity titled "Evaluations to Improve Prevention Interventions Under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" (Funding Opportunity Number RFA GH 17 001) is a discretionary funding announcement issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under the PEPFAR umbrella. It is structured as a cooperative agreement, meaning the CDC would not simply provide funds and step back, but would expect substantial involvement and collaboration during the life of the project, typically around study design alignment, evaluation standards, and use of findings for program decisions. The activity category is health, and it is associated with CFDA number 93.067.
The core purpose of the opportunity is to strengthen HIV prevention by identifying what drives HIV acquisition risk most strongly among adolescent girls and young women (AGYW) ages 15 to 24 in sub-Saharan Africa, particularly in a community with a high HIV burden. The announcement is grounded in the reality that AGYW in this region face disproportionately high HIV incidence and that their vulnerability is shaped by a wide range of interacting factors. These factors can include biological influences, individual behaviors, relationship dynamics, and broader community and structural conditions such as poverty, gender inequality, violence, mobility, school dropout, transactional sex, age-disparate partnerships, limited access to prevention and health services, and social norms that reduce agency or negotiating power. The FOA is essentially calling for a rigorous evaluation approach that can tease apart which single factor, or which combination of factors, best predicts HIV acquisition risk in the target setting. The practical intent is to help PEPFAR and partners focus prevention resources on the most predictive and actionable drivers of risk, rather than spreading investments across many possible correlates without clarity on which ones matter most.
In terms of what the work is meant to produce, the emphasis is on predictive insight that improves prevention programming. The findings are expected to inform evidence-based interventions at multiple levels: individual-level strategies (such as testing uptake, PrEP access, adherence support, sexual health education), relationship-level approaches (partner services, interventions addressing age-disparate relationships, violence prevention), and community or structural interventions (school retention initiatives, economic strengthening, stigma reduction, service integration, and improvements in youth-friendly care). While the immediate focus is AGYW in a high-burden community, the FOA also signals that future studies could expand beyond this group, either to other high-risk populations in high-burden communities or to AGYW in additional communities, implying that this award is part of a broader learning agenda where early evaluation results can shape subsequent research and program design.
The eligible applicant pool is broad and includes many types of U.S. and non-U.S. entities commonly involved in public health research and implementation. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofit organizations with 501(c)(3) status (other than universities); for-profit organizations (including small businesses); and other entities as described in the additional eligibility text. This wide eligibility reflects the interdisciplinary and cross-sector nature of HIV prevention evaluation, where strong proposals could come from universities, research institutes, implementers, health departments, or partnerships that combine program reach with analytic expertise.
The award information indicates an anticipated single award (Expected Awards: 1) with an award ceiling of $1,500,000. The opportunity was created on October 14, 2016, with an original closing date of December 14, 2016, and the application submission deadline was 5:00 p.m. Eastern Time on the due date for electronic submissions. Overall, the opportunity represents a targeted investment to generate clearer, decision-ready evidence about what most strongly predicts HIV acquisition among AGYW in high-burden settings, with the goal of improving the effectiveness and efficiency of PEPFAR-supported prevention interventions.Apply for RFA GH 17 001
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Evaluations to Improve Prevention Interventions Under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Oct 14, 2016.
- Applicants must submit their applications by Dec 14, 2016 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Frequently Asked Questions (FAQs)
1) What is the title of this grant opportunity?
The opportunity is titled "Evaluations to Improve Prevention Interventions Under the Presidents Emergency Plan for AIDS Relief (PEPFAR)."
2) What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA GH 17 001.
3) Which federal agency is offering this opportunity?
This is a discretionary funding announcement from the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), under the PEPFAR umbrella.
4) What type of award is this?
This opportunity is structured as a cooperative agreement.
5) What does "cooperative agreement" mean in this context?
A cooperative agreement indicates that CDC expects substantial involvement during the project period. The description notes that CDC involvement would typically include collaboration and alignment on elements such as study design, evaluation standards, and the use of findings for program decisions, rather than simply providing funds without ongoing engagement.
6) What is the activity category for this funding?
The activity category is health.
7) What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA number 93.067.
8) What is the overall purpose of this grant?
The core purpose is to strengthen HIV prevention by identifying which factors most strongly drive HIV acquisition risk among adolescent girls and young women (AGYW) ages 15 to 24 in sub-Saharan Africa, particularly in a community with a high HIV burden.
9) Who is the primary population of interest?
The primary population of interest is adolescent girls and young women (AGYW) ages 15 to 24.
10) Where is the work intended to focus geographically?
The focus is sub-Saharan Africa, particularly a community with a high HIV burden.
11) Why does the announcement focus on AGYW in sub-Saharan Africa?
The announcement is grounded in the reality that AGYW in this region experience disproportionately high HIV incidence, and that vulnerability is shaped by multiple interacting factors across biological, behavioral, relationship, community, and structural levels.
12) What kinds of risk drivers does the announcement mention?
The description lists a range of factors that can influence HIV risk, including biological influences, individual behaviors, relationship dynamics, and broader community and structural conditions. Examples mentioned include poverty, gender inequality, violence, mobility, school dropout, transactional sex, age-disparate partnerships, limited access to prevention and health services, and social norms that reduce agency or negotiating power.
13) What is CDC/PEPFAR looking for the evaluation to determine?
The announcement calls for a rigorous evaluation approach that can tease apart which single factor, or which combination of factors, best predicts HIV acquisition risk in the target setting.
14) Is the goal to list all possible risk factors or to prioritize them?
Based on the description, the practical intent is to prioritize which drivers are most predictive and actionable, so prevention resources can be focused on what matters most rather than being spread across many possible correlates without clarity.
15) What kinds of outcomes or deliverables are emphasized?
The emphasis is on producing predictive insight that improves prevention programming. The findings are expected to be decision-ready evidence that can inform where and how prevention resources are targeted.
16) How are the findings expected to be used?
The findings are expected to inform evidence-based HIV prevention interventions and program decisions supported by PEPFAR and partners.
17) What levels of prevention intervention are mentioned as being informed by the findings?
The description indicates findings may inform interventions at multiple levels: individual-level strategies, relationship-level approaches, and community or structural interventions.
18) What are examples of individual-level strategies mentioned?
Examples listed include testing uptake, PrEP access, adherence support, and sexual health education.
19) What are examples of relationship-level approaches mentioned?
Examples listed include partner services, interventions addressing age-disparate relationships, and violence prevention.
20) What are examples of community or structural interventions mentioned?
Examples listed include school retention initiatives, economic strengthening, stigma reduction, service integration, and improvements in youth-friendly care.
21) Is this opportunity limited to only AGYW in a single community?
The immediate focus described is AGYW in a high-burden community. The announcement also signals that future studies could expand beyond this group (for example, to other high-risk populations in high-burden communities or to AGYW in additional communities), suggesting this award contributes to a broader learning agenda.
22) How many awards are expected to be made?
The award information indicates an anticipated single award (Expected Awards: 1).
23) What is the maximum funding amount (ceiling) for this award?
The award ceiling is $1,500,000.
24) Who is eligible to apply?
The eligible applicant pool is broad and includes U.S. and non-U.S. entities commonly involved in public health research and implementation.
25) What types of government entities are eligible?
Eligible applicants include state, county, and local governments; special district governments; and independent school districts.
26) Are higher education institutions eligible?
Yes. Eligible applicants include public and state-controlled institutions of higher education as well as private institutions of higher education.
27) Are tribal governments and tribal organizations eligible?
Yes. Eligible applicants include federally recognized Native American tribal governments and other tribal organizations.
28) Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
29) Are nonprofit organizations eligible?
Yes. Nonprofit organizations with 501(c)(3) status (other than universities) are included in the eligible applicant pool.
30) Are for-profit organizations eligible?
Yes. For-profit organizations (including small businesses) are listed as eligible applicants.
31) When was this funding opportunity created?
The opportunity was created on October 14, 2016.
32) What was the original closing date?
The original closing date was December 14, 2016.
33) What time was the application due on the deadline date?
The application submission deadline was 5:00 p.m. Eastern Time on the due date for electronic submissions.
34) What is the main value of this opportunity for prevention programming?
The opportunity represents a targeted investment to generate clearer evidence about what most strongly predicts HIV acquisition among AGYW in high-burden settings, with the goal of improving the effectiveness and efficiency of PEPFAR-supported HIV prevention interventions.
Browse more opportunities from the same category: Health
Next opportunity: Wildlife Restoration, Sport Fish Restoration and State Wildlife Grant Programs
Previous opportunity: Provision of Comprehensive Public health Services for the fishing Communities in the Republic of Uganda under PEPFAR
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA GH 17 001
Applicants also applied for:
Applicants who have applied for this opportunity (RFA GH 17 001) also looked into and applied for these:
| Funding Opportunity |
|---|
| Local non-governmental partnerships for sustained country leadership in Uganda under PEPFAR Apply for CDC RFA GH14 141203CONT17 Funding Number: CDC RFA GH14 141203CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Support Uganda’s Ministry of Health’s capacity to address HIV response through strengthening health systems in the Republic of Uganda under President Emergency Plan for AIDS Relief Apply for CDC RFA GH12 121605CONT17 Funding Number: CDC RFA GH12 121605CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Development of a Laboratory Network and Society to Implement a Quality Systems Program Toward Accreditation and Laboratory Management under the President’s Emergency Plan for AIDS Relief Apply for CDC RFA GH12 120105CONT17 Funding Number: CDC RFA GH12 120105CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Supporting Laboratory Strengthening Activities in Resource-Limited Countries under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH13 136604CONT17 Funding Number: CDC RFA GH13 136604CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Strengthening Public Health Systems in the Caribbean by supporting the Caribbean Public Health Agency (CARPHA) under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH14 140404CONT17 Funding Number: CDC RFA GH14 140404CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Increasing capacity of the Dominican Republic’s Ministry of Health in the areas of Blood Safety, Monitoring and Evaluation, Epidemiology and Heath Information Systems under PEPFAR) Apply for CDC RFA GH15 151803CONT17 Funding Number: CDC RFA GH15 151803CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Improving HIV/STI/TB Prevention, Treatment and Care Services for Mobile Populations in the Dominican Republic under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 151703CONT17 Funding Number: CDC RFA GH15 151703CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Improving PMTCT and Quality of HIV Treatment and STI Surveillance and Increasing Capacity to address needs for key populations in the Dominican Republic Ministry of Health under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 152003CONT17 Funding Number: CDC RFA GH15 152003CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| USAID CARING FOR VULNERABLE CHILDREN (Ethiopia OVC ACTIVITY) Apply for RFA 663 16 000009 Funding Number: RFA 663 16 000009 Agency: Agency for International Development, Ethiopia USAID-Addis Ababa Category: Health Funding Amount: $49,800,000 |
| Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance Apply for HRSA 17 046 Funding Number: HRSA 17 046 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
| Provide Accreditation and Quality Management Services to National Blood Services in Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 153403CONT17 Funding Number: CDC RFA GH15 153403CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Advanced Nursing Education Workforce (ANEW) Program Apply for HRSA 17 067 Funding Number: HRSA 17 067 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Integrated Economic, Dynamic Disease, Risk and Decision Analytic Modeling of Global and Domestic Apply for CDC RFA GH16 160202CONT17 Funding Number: CDC RFA GH16 160202CONT17 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Maternal and Child Environmental Health Network Apply for HRSA 17 081 Funding Number: HRSA 17 081 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Creation of a Healthcare-Associated Infectious Disease Modeling Network to Improve Prevention Research and Healthcare Delivery Apply for RFA CK 17 001 Funding Number: RFA CK 17 001 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $650,000 |
| Centers of Excellence (COE) Apply for HRSA 17 065 Funding Number: HRSA 17 065 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Cooperative Agreements for Adolescent and Transitional Aged Youth Treatment Implementation (Short Title: Youth Treatment - Implementation) Apply for TI 17 002 Funding Number: TI 17 002 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $800,000 |
| Maternal and Child Environmental Health Collaborative Improvement and Innovation Network (CoIIN) Apply for HRSA 17 093 Funding Number: HRSA 17 093 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Understanding the Effects of ApoE2 on the Interaction between Aging and Alzheimers Disease (R01) Apply for RFA AG 17 056 Funding Number: RFA AG 17 056 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $300,000 |
| Determining and Monitoring Health Conditions Identified in the Medical Assessment of US-Bound Refugees Apply for RFA CK 17 004 Funding Number: RFA CK 17 004 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $2,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA GH 17 001", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.