Opportunity Information: Apply for PAR 19 051
The Emerging Global Leader Award (K43 Independent Clinical Trial Required), funding opportunity number PAR 19 051, is a National Institutes of Health (NIH) discretionary grant program designed to support the career development of promising researchers based in low- or middle-income countries (LMICs). It is a reissue of the NIH Emerging Global Leader Program (K43) that was updated specifically to align with NIH clinical trials policy, meaning the opportunity is intended for applicants whose proposed research and career development plan includes conducting an independent clinical trial as part of the award.
A central goal of this program is to help build and sustain research leadership and long-term scientific capacity within LMIC institutions by providing support to investigators who are positioned to become independent, internationally competitive research leaders. While the listing describes it under the broad funding activity category of education, environment, and health, the involvement of multiple CFDA numbers (93.113, 93.121, 93.172, 93.242, 93.313, 93.398, 93.853, 93.989) signals that the opportunity can align with a wide range of NIH mission areas spanning global health and biomedical research topics, depending on the participating NIH Institutes and Centers and the scientific focus of a specific application.
Eligibility is narrowly defined and is one of the most important features of this announcement. Only non-domestic (non-U.S.) entities that are foreign institutions located in low- or middle-income countries are eligible to apply. In other words, the applicant organization must be a foreign institution in an LMIC. At the same time, non-domestic components of U.S. organizations are explicitly not eligible to apply, which prevents a U.S.-based organization from applying through an overseas branch, affiliate, or similar non-U.S. component. The notice also states that foreign components, as defined in the NIH Grants Policy Statement, are allowed. This typically means an application may include certain aspects of the work being carried out by a foreign component consistent with NIH policy, but this allowance does not change the core requirement that the applicant institution itself must be a qualifying foreign institution in an LMIC. The opportunity also lists public and state-controlled institutions of higher education among eligible applicants, which generally aligns with universities and similar public institutions, but the controlling limitation remains the LMIC foreign-institution requirement described above.
From an administrative standpoint, this opportunity is offered as a grant mechanism. The sponsoring agency is the NIH. The creation date in the source data is November 2, 2018, and the original closing date listed is November 4, 2020. The source data does not provide an award ceiling or the expected number of awards, indicating those details are either not specified here or are provided in the full funding announcement. For applicants, that means budgeting expectations and competitiveness factors would need to be verified in the complete announcement text and any related NIH guide notices.
Overall, this funding opportunity supports LMIC-based investigators who are ready to transition into independent research leadership roles and who will conduct an independent clinical trial under the K43 framework. The defining constraints are the applicant institution location and status (foreign institution in an LMIC), the exclusion of non-U.S. components of U.S. organizations as applicants, and the clinical-trial-required nature of the program as revised to match NIH policy. For final confirmation of institutional eligibility, allowable project structures, and clinical trial expectations, applicants are directed to consult the full funding announcement and NIH Grants Policy Statement definitions referenced in the description.Apply for PAR 19 051
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Emerging Global Leader Award (K43 Independent Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.242, 93.313, 93.398, 93.853, 93.989.
- This funding opportunity was created on 2018-11-02.
- Applicants must submit their applications by 2020-11-04. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education.
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Frequently Asked Questions (FAQs): Emerging Global Leader Award (K43 Independent Clinical Trial Required) - PAR 19-051
What is the Emerging Global Leader Award (K43 Independent Clinical Trial Required)?
The Emerging Global Leader Award (K43 Independent Clinical Trial Required) is an NIH discretionary grant program designed to support the career development of promising researchers who are based at institutions in low- or middle-income countries (LMICs). It aims to help investigators transition toward independent, internationally competitive research leadership roles.
What is the funding opportunity number for this program?
The funding opportunity number is PAR 19-051.
Which federal agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Is this opportunity a grant or a contract?
This opportunity is offered as a grant mechanism.
Who is the program intended to support?
It is intended to support promising LMIC-based researchers who are positioned to become independent research leaders and who will use the award to develop their careers while building research leadership and long-term scientific capacity within LMIC institutions.
What is the main goal of the program?
A central goal is to build and sustain research leadership and long-term scientific capacity within LMIC institutions by supporting investigators as they develop into independent, internationally competitive research leaders.
Does the proposed work need to include a clinical trial?
Yes. This K43 opportunity was updated to align with NIH clinical trials policy and is intended for applicants whose proposed research and career development plan includes conducting an independent clinical trial as part of the award.
Why does the announcement say it is a reissue?
It is described as a reissue of the NIH Emerging Global Leader Program (K43) that was updated specifically to align with NIH clinical trials policy. In practical terms, the updated version is structured for applications that include an independent clinical trial.
Which organizations are eligible to apply?
Only non-domestic (non-U.S.) entities that are foreign institutions located in low- or middle-income countries (LMICs) are eligible to apply. The applicant organization must be a qualifying foreign institution in an LMIC.
Can a U.S. organization apply through its overseas branch or affiliate?
No. Non-domestic components of U.S. organizations are explicitly not eligible to apply. This prevents a U.S.-based organization from applying through an overseas branch, affiliate, or similar non-U.S. component.
Are public or state-controlled universities eligible?
Public and state-controlled institutions of higher education are listed among eligible applicants, but the controlling limitation is that the applicant institution must be a foreign institution located in an LMIC.
What does it mean that "foreign components" are allowed?
The description states that foreign components (as defined in the NIH Grants Policy Statement) are allowed. This generally means certain aspects of the work may be carried out by a foreign component consistent with NIH policy. However, this does not change the core requirement that the applicant institution itself must be a qualifying foreign institution in an LMIC.
What research areas can be supported under this opportunity?
The opportunity can align with a wide range of NIH mission areas spanning global health and biomedical research topics, depending on the participating NIH Institutes and Centers and the scientific focus of a specific application.
What are the CFDA numbers associated with this opportunity?
The associated CFDA numbers listed are 93.113, 93.121, 93.172, 93.242, 93.313, 93.398, 93.853, and 93.989.
Does the listing specify an award ceiling?
No. The source information provided does not include an award ceiling.
Does the listing specify the expected number of awards?
No. The source information provided does not specify the expected number of awards.
Where should applicants look for budgeting expectations and competitiveness details?
Since the award ceiling and expected number of awards are not provided in the source information, applicants would need to verify budgeting expectations and competitiveness factors in the full funding announcement and any related NIH guide notices.
What are the key eligibility constraints to focus on?
The defining constraints are: (1) the applicant institution must be a foreign institution in an LMIC, (2) non-U.S. components of U.S. organizations cannot apply, and (3) the program is clinical-trial-required, meaning an independent clinical trial is part of the intended scope.
What are the key dates mentioned in the source information?
The creation date in the source data is November 2, 2018, and the original closing date listed is November 4, 2020.
Is the closing date definitive based on the information provided?
The information provided lists an original closing date (November 4, 2020). For current status, dates, and any updates or extensions, applicants are directed to consult the full funding announcement and related NIH notices.
What should applicants consult for final confirmation of eligibility and clinical trial expectations?
Applicants should consult the full funding announcement and the NIH Grants Policy Statement definitions referenced in the description for final confirmation of institutional eligibility, allowable project structures, and clinical trial expectations.
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| Funding Opportunity |
|---|
| Research Project Grant (Parent R01 Clinical Trial Required) Apply for PA 19 055 Funding Number: PA 19 055 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) Apply for PA 19 053 Funding Number: PA 19 053 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) Apply for PA 19 054 Funding Number: PA 19 054 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) Apply for PA 19 052 Funding Number: PA 19 052 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $50,000 |
| NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) Apply for PA 19 091 Funding Number: PA 19 091 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required) Apply for PA 19 092 Funding Number: PA 19 092 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Basic Experimental Studies with Humans Required) Apply for PA 19 088 Funding Number: PA 19 088 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) Apply for PAR 19 098 Funding Number: PAR 19 098 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required) Apply for PA 19 121 Funding Number: PA 19 121 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) Apply for PA 19 122 Funding Number: PA 19 122 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Required) Apply for PA 19 131 Funding Number: PA 19 131 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed) Apply for PA 19 132 Funding Number: PA 19 132 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| U.S.-China Program for Biomedical Collaborative Research (R01 Clinical Trial Optional) Apply for RFA CA 19 009 Funding Number: RFA CA 19 009 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $150,000 |
| Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) Apply for PAR 19 158 Funding Number: PAR 19 158 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (Clinical Trials Not Allowed R25) Apply for PAR 19 164 Funding Number: PAR 19 164 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) Apply for PA 19 187 Funding Number: PA 19 187 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (R25 Clinical Trial Not Allowed) Apply for PAR 19 197 Funding Number: PAR 19 197 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Building Interdisciplinary Research Careers in Women's Health (BIRCWH); K12 Clinical Trial Optional Apply for RFA OD 19 020 Funding Number: RFA OD 19 020 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $600,000 |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R21 Clinical Trial Optional) Apply for PAR 19 252 Funding Number: PAR 19 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Influences on Aging: Effects of Extreme Weather and Disaster Events on Aging Populations (R01 Clinical Trial Optional) Apply for PAR 19 250 Funding Number: PAR 19 250 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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