Opportunity Information: Apply for PA 19 191

The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) is an NIH fellowship opportunity designed specifically for predoctoral students who are enrolled in dual-doctoral training pathways such as MD/PhD and other comparable combined clinical and research degree programs (including DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD, and similar tracks). The core aim is to strengthen the kind of tightly integrated training that physician- and clinician-scientists need, blending rigorous dissertation-focused research preparation with meaningful clinical development so that graduates are positioned to become productive, independent investigators with a foot firmly in both worlds. This FOA is meant to support students at institutions that already have NIH-funded institutional predoctoral dual-degree training programs, so it is targeted to settings with established infrastructure for this type of integrated training.

To be competitive, an applicant is expected to lay out two things in a cohesive way: first, a well-justified dissertation research project in a health-related scientific area that aligns with the missions of the participating NIH Institutes and Centers; and second, an integrated training plan that explains how the applicant will combine research training and clinical training across the fellowship period. The NIH emphasis here is not simply on funding a research project in isolation, but on showing that the fellowship will add clear value to the applicant’s overall development, particularly in ways that accelerate the transition into a long-term physician/clinician-scientist career. In other words, reviewers are looking for a plan that demonstrates thoughtful sequencing and integration of clinical responsibilities, research milestones, mentorship, and professional development so the applicant emerges with stronger independence, deeper scientific expertise, and a credible pathway toward a sustained research career.

There are also important boundaries around clinical trial involvement. Under this announcement, an applicant cannot propose to lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial as the primary driver of the application. However, the FOA does allow a fellow to gain research experience within a clinical trial that is led by a sponsor or co-sponsor, which means applicants can still build clinically relevant research skills and exposure to trial operations as long as they are not positioned as the person directing the trial itself. This distinction matters for applicants whose work intersects with clinical research, because it shapes what kinds of aims, methods, and roles can be proposed while remaining responsive to the FOA.

From an eligibility standpoint, the opportunity is administered by the National Institutes of Health and is listed as a discretionary grant mechanism in the education and health-related funding activity space. Eligible applicant organizations are broad and include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations other than small businesses, small businesses, and other categories specified by the FOA. The announcement explicitly highlights inclusion of organizations such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and eligible agencies of the federal government. At the same time, it draws clear lines regarding foreign involvement: non-U.S. (foreign) institutions are not eligible to apply as applicant organizations, and non-U.S. components of U.S. organizations are not eligible to apply; however, foreign components (as defined in the NIH Grants Policy Statement) are allowed, meaning certain aspects of the training or research could involve a foreign component if it fits NIH policy and is appropriately justified.

The specific FOA referenced is PA-19-191, created on February 22, 2019, with an original closing date listed as June 30, 2020. Multiple CFDA program numbers are associated with this opportunity, reflecting participation across a range of NIH institutes and programs in biomedical and health research. While the source data does not specify an award ceiling or expected number of awards in the excerpt provided, the overall structure and intent are clear: this is a fellowship mechanism focused on investing in the next generation of clinician-scientists by supporting a well-mentored dissertation project and a carefully designed, genuinely integrated clinical-research training experience at institutions with NIH-backed dual-degree training environments.

  • The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.233, 93.242, 93.273, 93.307, 93.351, 93.398, 93.837, 93.838, 93.839, 93.840, 93.847, 93.865, 93.866.
  • This funding opportunity was created on 2019-02-22.
  • Applicants must submit their applications by 2020-06-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NRSA Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) - PA-19-191

What is this funding opportunity?

This opportunity is the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for predoctoral students in dual-doctoral programs at institutions that already have NIH-funded institutional predoctoral dual-degree training programs. It is commonly referred to as the Parent F30 and is tied to FOA PA-19-191.

Who is this fellowship designed for?

It is designed for predoctoral students enrolled in dual-degree training pathways that combine a clinical/professional doctoral degree with a research doctorate. The description specifically mentions MD/PhD and comparable combined programs such as DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD, and similar tracks.

What is the main goal of the fellowship?

The central goal is to strengthen tightly integrated training for physician- and clinician-scientists by blending rigorous dissertation-focused research training with meaningful clinical development. The intended outcome is to position graduates to become productive, independent investigators with sustained careers that integrate research and clinical perspectives.

What kind of institution setting is this targeted to?

This FOA is targeted to students at institutions that already have NIH-funded institutional predoctoral dual-degree training programs. In other words, it is aimed at places with established infrastructure to support integrated clinical and research training.

What are the major pieces a competitive application needs to include?

The opportunity emphasizes two major components that need to fit together cohesively:

  • A well-justified dissertation research project in a health-related scientific area aligned with the missions of participating NIH Institutes and Centers.
  • An integrated training plan explaining how the applicant will combine research training and clinical training across the fellowship period.

Is the NIH mainly funding a research project, or a training experience?

Based on the description, the emphasis is not on funding a research project in isolation. Reviewers are looking for clear added value to the applicant's overall development as a physician/clinician-scientist, including thoughtful integration of clinical responsibilities, research milestones, mentorship, and professional development.

What does "integrated training plan" mean in this context?

It means the application should explain how clinical development and research training will be sequenced and blended over time during the fellowship period. The plan should show how mentorship, training activities, and milestones work together so the applicant progresses toward scientific independence while maintaining a credible clinician-scientist trajectory.

What research areas are considered appropriate?

The research is expected to be health-related and aligned with the missions of the participating NIH Institutes and Centers. The excerpt does not list specific topic areas, but it indicates the project should fit NIH mission priorities for the participating institutes/centers.

Are clinical trials allowed under this FOA?

There are limits. An applicant cannot propose to lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial as the primary focus of the application.

Can a fellow participate in a clinical trial in some way?

Yes. The FOA allows a fellow to gain research experience within a clinical trial that is led by a sponsor or co-sponsor. That means an applicant can build clinically relevant research experience and exposure to trial operations, as long as the fellow is not positioned as the person directing the trial itself.

Why does the clinical trial restriction matter for applicants?

Because it affects what roles and aims can be proposed while staying responsive to the FOA. If the proposed work intersects with clinical research, the application needs to be structured so the fellow is not the lead for an independent, feasibility, or ancillary clinical trial, even if the fellow is learning within a trial environment led by others.

Who administers this opportunity?

The opportunity is administered by the National Institutes of Health (NIH).

What type of funding mechanism is this described as?

It is described as a discretionary grant mechanism in the education and health-related funding activity space, and it is specifically an NRSA individual fellowship aimed at predoctoral dual-degree trainees.

What types of organizations are eligible to apply as the applicant organization?

The eligible applicant organizations are broad and include:

  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofits (including both 501(c)(3) and non-501(c)(3) entities)
  • For-profit organizations other than small businesses
  • Small businesses
  • Other categories specified by the FOA

Does the FOA specifically encourage or include certain types of institutions?

Yes. The announcement explicitly highlights inclusion of organizations such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and eligible agencies of the federal government.

Are foreign (non-U.S.) institutions allowed to apply?

No. Non-U.S. (foreign) institutions are not eligible to apply as applicant organizations, and non-U.S. components of U.S. organizations are not eligible to apply.

Is any foreign involvement allowed at all?

Yes. The FOA indicates that foreign components (as defined in the NIH Grants Policy Statement) are allowed. That suggests parts of the training or research could involve a foreign component if it is consistent with NIH policy and is appropriately justified.

What is the FOA number for this opportunity?

The specific FOA referenced is PA-19-191.

When was this FOA created, and what closing date is listed in the excerpt?

The excerpt states the FOA was created on February 22, 2019, and lists an original closing date of June 30, 2020.

Are specific CFDA numbers associated with this opportunity?

Yes. The excerpt notes that multiple CFDA program numbers are associated with this opportunity, reflecting participation across a range of NIH institutes and programs in biomedical and health research.

Does the excerpt specify an award ceiling or the expected number of awards?

No. The source data excerpt does not specify an award ceiling or an expected number of awards.

What is the overall intent of the program, based on the excerpt?

The overall intent is to invest in the next generation of clinician-scientists by supporting a well-mentored dissertation project and a carefully designed, genuinely integrated clinical-research training experience at institutions with NIH-backed dual-degree training infrastructure.

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Funding Number: PA 19 271
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PHS 2019-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed Apply for PA 19 270

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NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) Apply for PA 20 187

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Agency: National Institutes of Health
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NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 20 185

Funding Number: PA 20 185
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NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) Apply for PA 20 188

Funding Number: PA 20 188
Agency: National Institutes of Health
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Funding Number: PA 20 197
Agency: National Institutes of Health
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Funding Number: PA 20 207
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Funding Number: PA 20 206
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Funding Number: PA 20 203
Agency: National Institutes of Health
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Funding Number: PA 20 246
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